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Effect of life-sustaining treatment decision law on pediatric in-hospital cardiopulmonary resuscitation rate: A Korean population-based study

  • Author Footnotes
    1 Jaeyoung Choi and Ah Young Choi contributed equally to this work as co-first authors.
    Jaeyoung Choi
    Footnotes
    1 Jaeyoung Choi and Ah Young Choi contributed equally to this work as co-first authors.
    Affiliations
    Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Search for articles by this author
  • Author Footnotes
    1 Jaeyoung Choi and Ah Young Choi contributed equally to this work as co-first authors.
    Ah Young Choi
    Footnotes
    1 Jaeyoung Choi and Ah Young Choi contributed equally to this work as co-first authors.
    Affiliations
    Department of Pediatrics, Chungnam National University Hospital, Daejeon, Republic of Korea
    Search for articles by this author
  • Esther Park
    Affiliations
    Department of Pediatrics, Jeonbuk National University Children's Hospital, Jeonju, Republic of Korea
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  • Meong Hi Son
    Affiliations
    Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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  • Joongbum Cho
    Correspondence
    Corresponding author at: Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Republic of Korea.
    Affiliations
    Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Search for articles by this author
  • Author Footnotes
    1 Jaeyoung Choi and Ah Young Choi contributed equally to this work as co-first authors.

      Abstract

      Aim

      The 2018 life-sustaining treatment (LST) decision law is expected to improve end-of-life quality in Korea. This study evaluated the national effect of the LST decision law on the cardiopulmonary resuscitation (CPR) rate among pediatric patients who died during hospital admission.

      Methods

      This retrospective cohort study was based on the Korean National Health Insurance database. Pediatric admissions within 12 months before or after implementation of the LST decision law were compared, allowing a 1-month transition period (February 2018). The changes in mortality, CPR, and documentation of LST decision were evaluated.

      Results

      The CPR rate of patients who died in hospital decreased after establishment of the LST decision law (49.6 vs 43.4 %, P = 0.04), without change of in-hospital mortality between pre/post-LST decision law activation (0.83 vs 0.81 per 1000 admissions, P = 0.67). In addition, in-hospital CPR (0.73 vs 0.67 per 1000 admissions, P = 0.15) and survival to discharge after in-hospital CPR (43.6 vs 47.2 %, P = 0.27) were slightly improved, although there was no statistical significance. Patients with LST decision documentation were less frequently mechanically ventilated (69.8 % vs 80.4 %, P < 0.01) and used fewer inotropes (76.5 % vs 90.1 %, P < 0.01) and more frequent opioids (67.1 % vs 57.4 %, P = 0.04).

      Conclusions

      The legally guided process of LST decision can decrease the CPR rate of children who die in hospitals. This result highlights the possibility of improving end-of-life quality by reducing non-beneficial in-hospital CPR.

      Keywords

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