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“Are out-of-hospital cardiac arrest outcomes really unpredictable?”

      Despite improvements in the management of out-of-hospital cardiac arrest (OHCA), short- and long-term outcomes remain disappointing.
      • Berger S.
      Survival from out-of-hospital cardiac arrest: Are we beginning to see progress?.
      • Berdowski J.
      • Berg R.A.
      • Tijssen J.G.P.
      • Koster R.W.
      Global incidences of out-of-hospital cardiac arrest and survival rates: systematic review of 67 prospective studies.
      OHCA still represents a leading cause of mortality, morbidity, and disability-adjusted life-years around the World.
      • Coute R.A.
      • Nathanson B.H.
      • Panchal A.R.
      • et al.
      Disability-adjusted life years following adult out-of-hospital cardiac arrest in the United States: a burden of disease estimate.
      • Callaway C.W.
      • Donnino M.W.
      • Fink E.L.
      • et al.
      Part 8: Post-cardiac arrest care: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.
      In this issue of Resuscitation, Byrne and associates present a compelling approach to predict both, short- and long-term mortality, as well as neurological outcomes for OHCA patients.
      • Byrne C.
      • Barcella C.A.
      • Lukacs Krogager M.
      • et al.
      Resuscitation external validation of the simple null-please clinical score in predicting outcomes of out-of-hospital cardiac arrest in the Danish population-a nationwide registry-based study.
      These investigators used an early attainable, easy, and highly reproducible prognostic tool that can potentially support clinical decision-making, prognostic objectivization, and resource allocation.

      Keywords

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      References

        • Berger S.
        Survival from out-of-hospital cardiac arrest: Are we beginning to see progress?.
        J Am Heart Assoc. 2017; 6e007469
        • Berdowski J.
        • Berg R.A.
        • Tijssen J.G.P.
        • Koster R.W.
        Global incidences of out-of-hospital cardiac arrest and survival rates: systematic review of 67 prospective studies.
        Resuscitation. 2010; 81: 1479-1487
        • Coute R.A.
        • Nathanson B.H.
        • Panchal A.R.
        • et al.
        Disability-adjusted life years following adult out-of-hospital cardiac arrest in the United States: a burden of disease estimate.
        Circ Cardiovasc Qual Outcomes. 2019; 12e004677
        • Callaway C.W.
        • Donnino M.W.
        • Fink E.L.
        • et al.
        Part 8: Post-cardiac arrest care: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.
        Circulation. 2015; 132: S465-S482
        • Byrne C.
        • Barcella C.A.
        • Lukacs Krogager M.
        • et al.
        Resuscitation external validation of the simple null-please clinical score in predicting outcomes of out-of-hospital cardiac arrest in the Danish population-a nationwide registry-based study.
        Resuscitation. 2022; 180: 128-136
        • Heo W.Y.
        • Jung Y.H.
        • Lee H.Y.
        • et al.
        External validation of cardiac arrest-specific prognostication scores developed for early prognosis estimation after out-of-hospital cardiac arrest in a Korean multicenter cohort.
        PLoS ONE. 2022; 17e0265275
        • Dumas F.
        • Paoli A.
        • Paul M.
        • et al.
        Association between previous health condition and outcome after cardiac arrest.
        Resuscitation. 2021; 167: 267-273
        • Sandroni C.
        • Cariou A.
        • Cavallaro F.
        • et al.
        Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine.
        Intensive Care Med. 2014; 40: 1816-1831
        • Aschauer S.
        • Dorffner G.
        • Sterz F.
        • Erdogmus A.
        • Laggner A.
        A prediction tool for initial out-of-hospital cardiac arrest survivors.
        Resuscitation. 2014; 85: 1225-1231
        • Balan P.
        • Hsi B.
        • Thangam M.
        • et al.
        The cardiac arrest survival score: A predictive algorithm for in-hospital mortality after out-of-hospital cardiac arrest.
        Resuscitation. 2019; 144: 46-53
        • Adrie C.
        • Cariou A.
        • Mourvillier B.
        • et al.
        Predicting survival with good neurological recovery at hospital admission after successful resuscitation of out-of-hospital cardiac arrest: The OHCA score.
        Eur Heart J. 2006; 27: 2840-2845
        • Maupain C.
        • Bougouin W.
        • Lamhaut L.
        • et al.
        The CAHP (Cardiac Arrest Hospital Prognosis) score: a tool for risk stratification after out-of-hospital cardiac arrest.
        Eur Heat J. 2016; 37: 3222-3228
        • Bae D.H.
        • Lee H.Y.
        • Jung Y.H.
        • et al.
        PROLOGUE (prognostication using logistic regression model for unselected adult cardiac arrest patients in the early stages): Development and validation of a scoring system for early prognostication in unselected adult cardiac arrest patients.
        Resuscitation. 2021; 159: 60-68
        • Martinell L.
        • Nielsen N.
        • Herlitz J.
        • et al.
        Early predictors of poor outcome after out-of-hospital cardiac arrest.
        Crit Care. 2017; 21: 96
        • Ahmad R.
        • Lumley S.
        • Lau Y.C.
        NULL-PLEASE: A new ‘Futility score’ in the management of survivors of out-of-hospital cardiac arrest.
        Resuscitation. 2016; 106e83
        • Potpara T.S.
        • Mihajlovic M.
        • Stankovic S.
        • et al.
        External validation of the simple NULL-PLEASE clinical score in predicting outcome of out-of-hospital cardiac arrest.
        Am J Med. 2017; 130: 1464.e13-1464.e21
        • Pham V.
        • Laghlam D.
        • Varenne O.
        • et al.
        Performance of OHCA, NULL-PLEASE and CAHP scores to predict survival in Out-of-Hospital Cardiac Arrest due to acute coronary syndrome.
        Resuscitation. 2021; 166: 31-37
        • Guy A.
        • Kawano T.
        • Besserer F.
        • et al.
        The relationship between no-flow interval and survival with favorable neurological outcome in out-of-hospital cardiac arrest: Implications for outcomes and ECPR eligibility.
        Resuscitation. 2020; 155: 219-225
        • Civil I.D.
        • Prescott R.J.
        Timing is everything: Do we need more from our databases?.
        Injury. 2018; 49: 1639-1640