Abstract
Background
Various methods have been used to control body temperature in targeted temperature
management (TTM), but few studies have compared specific subtypes of surface cooling
systems. The aim of this study was to compare the efficiencies and neurological outcomes
between hydrogels pad and water-circulating blanket cooling methods.
Methods
We conducted a multicentre, prospective, registry-based study of out-of-hospital cardiac
arrest patients treated with TTM between 2015 and 2018. We compared the neurological
outcomes, efficacies for cooling, and adverse events between patients who received
TTM using a hydrogel pad and water-circulating blanket cooling. Patients were one-to-one
matched using propensity scores to adjust for differences in the baseline characteristics
of each cooling method. The primary outcome was a favourable neurological outcome
at 6 months.
Results
We included 1,132 patients in the analysis, 870 of whom underwent hydrogel pad cooling,
and the remaining 262 underwent water-circulating blanket cooling. In the unmatched
cohort, a greater number of adverse events occurred in the water-circulating blanket
group. The favourable neurologic outcome rates at 6 months were similar between the
hydrogel pad group and the water circulating blanket group (30.2% vs. 29.8%, p = 0.939). In the propensity-matched cohort, which included 184 pairs, the rates of
adverse events between the two groups were similar. The similarity of favourable neurologic
outcome rates at 6 months between the two groups persisted (28.8% vs. 29.9%, p = 0.819).
Conclusion
Neurological outcomes and adverse events between the hydrogel pad cooling and water-circulating
blanket cooling groups were similar.
Keywords
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Article info
Publication history
Published online: October 19, 2021
Accepted:
October 11,
2021
Received in revised form:
October 8,
2021
Received:
September 9,
2021
Identification
Copyright
© 2021 Elsevier B.V. All rights reserved.
