Advertisement
Clinical paper| Volume 169, P175-181, December 2021

Applying a set of termination of resuscitation criteria to paediatric out-of-hospital cardiac arrest

      Abstract

      Objective

      Prehospital Termination of Resuscitation (TOR) protocols for adults can reduce the number of futile transports of patients in cardiac arrest, yet similar protocols are not widely available for paediatric out-of-hospital cardiac arrest (POHCA). The objective of this study was to apply a set of criteria for paediatric TOR (pTOR) from the Maryland Institute for Emergency Medical Services Systems (MIEMSS) to a large national cohort and determine its association with return of spontaneous circulation (ROSC) after POHCA.

      Methods

      We identified patients ages 0–17 treated by Emergency Medical Services (EMS) with cardiac arrest in 2019 from the ESO dataset and and applied the applicable pTOR certeria for medical or traumatic arrests. We calculated predictive test characteristics for the outcome of prehospital ROSC, stratified by medical and traumatic cause of arrest.

      Results

      We analyzed records for 1595 POHCA patients. Eighty-eight percent (n = 1395) were classified as medical. ROSC rates were 23% among medical POHCA and 27% among traumatic POHCA. The medical criteria correctly classified >99% (322/323) of patients who achieved ROSC as ineligible for TOR. The trauma criteria correctly classified 93% (50/54) of patients with ROSC as ineligible for TOR. Of the five misclassified patients, three were involved in drowning incidents.

      Conclusions

      The Maryland pTOR criteria identified eligible patients who did not achieve prehospital ROSC, while reliably excluding those who did achieve prehospital ROSC. As most misclassified patients were victims of drowning, we recommend considering the exclusion of drowning patients from future pTOR guidelines. Further studies are needed to evaluate the long-term survival and neurologic outcome of patients misclassified by pTOR criteria.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Resuscitation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Millin M.G.
        • Khandker S.R.
        • Malki A.
        Termination of resuscitation of nontraumatic cardiopulmonary arrest: resource document for the National Association of EMS Physicians position statement.
        Prehosp Emerg Care. 2011; 15: 547-554
        • Richman P.B.
        • Vadeboncoeur T.F.
        • Chikani V.
        • Clark L.
        • Bobrow B.J.
        Independent evaluation of an out-of-hospital termination of resuscitation (TOR) clinical decision rule.
        Acad Emerg Med. 2008; 15: 517-521
        • Morrison L.J.
        • Eby D.
        • Veigas P.V.
        • et al.
        Implementation trial of the basic life support termination of resuscitation rule: reducing the transport of futile out-of-hospital cardiac arrests.
        Resuscitation. 2014; 85: 486-491
        • Sasson C.
        • Hegg A.J.
        • Macy M.
        • et al.
        Prehospital termination of resuscitation in cases of refractory out-of-hospital cardiac arrest.
        JAMA. 2008; 300: 1432-1438
        • Ruygrok M.L.
        • Byyny R.L.
        • Haukoos J.S.
        Colorado Cardiac Arrest & Resuscitation Collaborative Study Group and the Denver Metro EMS Medical Directors. Validation of 3 termination of resuscitation criteria for good neurologic survival after out-of-hospital cardiac arrest.
        Ann Emerg Med. 2009; 54: 239-247
      1. American College of Surgeons Committee on Trauma; American College of Emergency Physicians Paediatric Emergency Medicine Committee; National Association of EMS Physicians; American Academy of Paediatrics Committee on Paediatric Emergency Medicine, Fallat ME. Withholding or termination of resuscitation in paediatric out-of-hospital traumatic cardiopulmonary arrest. Ann Emerg Med. 2014;63:504–15.

        • Millin M.G.
        • Galvagno S.M.
        • Khandker S.R.
        • Malki A.
        • Bulger E.M.
        Standards and Clinical Practice Committee of the National Association of EMS Physicians (NAEMSP); Subcommittee on Emergency Services-Prehospital of the American College of Surgeons’ Committee on Trauma (ACSCOT). Withholding and termination of resuscitation of adult cardiopulmonary arrest secondary to trauma: resource document to the joint NAEMSP-ACSCOT position statements.
        J Trauma Acute Care Surg. 2013; 75: 459-467
        • National Association of EMS Physicians
        Termination of resuscitation in nontraumatic cardiopulmonary arrest.
        Prehosp Emerg Care. 2011; 15: 542
        • Muñoz M.G.
        • Beyda D.H.
        An ethical justification for termination of resuscitation protocols for paediatric patients.
        Pediatr Emerg Care. 2017; 33: 505-515
        • Benjamin E.J.
        • Virani S.S.
        • Callaway C.W.
        • et al.
        American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association.
        Circulation. 2018; 137: e67-e492
        • Hawkes C.
        • Booth S.
        • Ji C.
        • Brace-McDonnell S.J.
        • Whittington A.
        • Mapstone J.
        • OHCAO collaborators
        Epidemiology and outcomes from out-of-hospital cardiac arrests in England.
        Resuscitation. 2017; 110: 133-140
        • Pemberton K.
        • Bosley E.
        • Franklin R.C.
        • Watt K.
        Epidemiology of pre-hospital outcomes of out-of-hospital cardiac arrest in Queensland, Australia.
        Emerg Med Australas. 2019; 31: 821-829
        • Haukoos J.S.
        • Witt G.
        • Gravitz C.
        • et al.
        Colorado Cardiac Arrest & Resuscitation Collaborative Study Group; Denver Metro EMS Medical Directors. Out-of-hospital cardiac arrest in Denver, Colorado: epidemiology and outcomes.
        Acad Emerg Med. 2010; 17: 391-398
      2. The Maryland Medical protocols for Emergency Medical Services. Effective August1, 2020 [Accessed June 1st, 2021 at: https://www.miemss.org/home/Portals/0/Docs/Guidelines_Protocols/MD-Medical-Protocols-2020-20200610.pdf?ver=2020-06-12-120333-457].

      3. NEMSIS Data Dictionary; NHTSA V 3.5.0(Accessed February 15, 2021 at: https://nemsis.org/media/nemsis_v3/release-3.5.0/DataDictionary/PDFHTML/EMSDEMSTATE/index.html.)

        • Shibahashi K.
        • Sugiyama K.
        • Hamabe Y.
        Paediatric out-of-hospital traumatic cardiopulmonary arrest after traffic accidents and termination of resuscitation.
        Ann Emerg Med. 2020; 75: 57-65
        • Schneiderman L.J.
        • Jecker N.S.
        • Jonsen A.R.
        Medical futility: its meaning and ethical implications.
        Ann Intern Med. 1990; 112: 949-954
        • Donoghue A.J.
        • Nadkarni V.
        • Berg R.A.
        • CanAm Paediatric Cardiac Arrest Investigators
        • et al.
        Out-of-hospital paediatric cardiac arrest: an epidemiologic review and assessment of current knowledge.
        Ann Emerg Med. 2005; 46: 512-522
        • Crewdson K.
        • Lockey D.
        • Davies G.
        Outcome from paediatric cardiac arrest associated with trauma.
        Resuscitation. 2007; 75: 29-34
        • Kieboom J.K.
        • Verkade H.J.
        • Burgerhof J.G.
        • et al.
        Outcome after resuscitation beyond 30 minutes in drowned children with cardiac arrest and hypothermia: Dutch nationwide retrospective cohort study.
        BMJ. 2015; 10h418
        • Tijssen J.A.
        • Prince D.K.
        • Morrison L.J.
        • Atkins D.L.
        • Austin M.A.
        • Berg R.
        • Resuscitation Outcomes Consortium
        • et al.
        Time on the scene and interventions are associated with improved survival in paediatric out-of-hospital cardiac arrest.
        Resuscitation. 2015; 94: 1-7
        • Banerjee P.R.
        • Ganti L.
        • Pepe P.E.
        • Singh A.
        • Roka A.
        • Vittone R.A.
        Early on-scene management of paediatric out-of-hospital cardiac arrest can result in improved likelihood for neurologically-intact survival.
        Resuscitation. 2019; 135: 162-167
        • Kiyohara K.
        • Okubo M.
        • Komukai S.
        • Izawa J.
        • Gibo K.
        • Matsuyama T.
        • et al.
        Association between resuscitative time on the scene and survival after paediatric out-of-hospital cardiac arrest.
        Circ Rep. 2021; 3: 211-216
        • Grunau B.
        • Kime N.
        • Leroux B.
        • et al.
        Association of intra-arrest transport vs continued on-scene resuscitation with survival to hospital discharge among patients with out-of-hospital cardiac arrest.
        JAMA. 2020; 324: 1058-1067
        • Cheskes S.
        • Byers A.
        • Zhan C.
        • Rescu Epistry Investigators
        • et al.
        CPR quality during out-of-hospital cardiac arrest transport.
        Resuscitation. 2017; 114: 34-39
        • Olasveengen T.M.
        • Wik L.
        • Steen P.A.
        Quality of cardiopulmonary resuscitation before and during transport in out-of-hospital cardiac arrest.
        Resuscitation. 2008; 76: 185-190
        • Fallat M.E.
        • Barbee A.P.
        • Forest R.
        • McClure M.E.
        • Henry K.
        • Cunningham M.R.
        During paediatric death in an out of hospital setting.
        Prehosp Emerg Care. 2016; 20: 798-807
        • Fallat M.E.
        • Barbee A.P.
        • Forest R.
        • McClure M.E.
        • Henry K.
        • Cunningham M.R.
        Perceptions by families of emergency medical service interventions during imminent paediatric out-of-hospital death.
        Prehosp Emerg Care. 2019; 23: 241-248
        • Hobgood C.
        • Mathew D.
        • Woodyard D.J.
        • Shofer F.S.
        • Brice J.H.
        Death in the field: teaching paramedics to deliver effective death notifications using the educational intervention “GRIEV_ING”.
        Prehosp Emerg Care. 2013; 17: 501-510
        • Campos A.
        • Ernest E.V.
        • Cash R.E.
        • et al.
        The Association of Death Notification and Related Training with Burnout among Emergency Medical Services Professionals.
        Prehosp Emerg Care. 2020; 20: 1-10
        • Atkins D.L.
        • Everson-Stewart S.
        • Sears G.K.
        • et al.
        Resuscitation Outcomes Consortium Investigators. Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest.
        Circulation. 2009; 119: 1484-1491
        • Tham L.P.
        • Chan I.
        Paediatric out-of-hospital cardiac arrests: epidemiology and outcome.
        Singapore Med J. 2005; 46: 289-296

      Linked Article