Out-of-hospital cardiac arrest (OHCA) carries a substantial health burden, with emergency
medical services (EMS) attending to 111 cases per 100,000 population annually.
1
Of EMS-treated cases, overall survival is approximately 10%.
- Virani S.S.
- Alonso A.
- Benjamin E.J.
- et al.
Heart disease and stroke statistics—2020 update: a report from the American Heart
Association.
Circulation. 2020; 141https://doi.org/10.1161/CIR.0000000000000757
1
When OHCA is witnessed however, many present with an initial shockable rhythm for
which prognosis can be substantially better, with the outcome being largely dependent
on the interval from collapse to defibrillation.
- Virani S.S.
- Alonso A.
- Benjamin E.J.
- et al.
Heart disease and stroke statistics—2020 update: a report from the American Heart
Association.
Circulation. 2020; 141https://doi.org/10.1161/CIR.0000000000000757
2
,
3
,
4
Upwards of three quarters may survive if the initial defibrillation occurs within
a few minutes of collapse. After the first few minutes, the chances of survival decline
by approximately 5–10% per minute that defibrillation is delayed, depending in part
on the provision of early CPR which can slow the ischemic insult of cardiovascular
collapse.
2
,
3
,
4
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References
- Heart disease and stroke statistics—2020 update: a report from the American Heart Association.Circulation. 2020; 141https://doi.org/10.1161/CIR.0000000000000757
- Predicting survival from out-of-hospital cardiac arrest: a graphic model.Ann Emerg Med. 1993; 22: 1652-1658
- The association between no-flow interval and neurological outcomes in out-of-hospital cardiac arrest: implications for rescuer response, initiating resuscitation, and ECPR candidacy evaluation.Resuscitation. 2019; 140: A235
- Cardiopulmonary resuscitation duration and survival in out-of-hospital cardiac arrest patients.Resuscitation. 2017; 111: 74-81https://doi.org/10.1016/j.resuscitation.2016.11.024
- Frank Pantridge.BMJ. 2005; 330: 793
- Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study.Lancet. 2019; 394: 2255-2262https://doi.org/10.1016/S0140-6736(19)32488-2
- The effects of public access defibrillation on survival after out-of-hospital cardiac arrest.Circulation. 2017; 136: 954-965https://doi.org/10.1161/CIRCULATIONAHA.117.029067
- Early cardiopulmonary resuscitation in out-of-hospital cardiac arrest.N Engl J Med. 2015; 372: 2307-2315https://doi.org/10.1056/NEJMoa1405796
- Overcoming spatial and temporal barriers to public access defibrillators via optimization.J Am Coll Cardiol. 2016; 68: 836-845https://doi.org/10.1016/j.jacc.2016.03.609
- Automated external defibrillators inaccessible to more than half of nearby cardiac arrests in public locations during evening, nighttime, and weekends.Circulation. 2013; 128: 2224-2231https://doi.org/10.1161/CIRCULATIONAHA.113.003066
- Public defibrillator accessibility and mobility trends during the COVID-19 pandemic in Canada.Resuscitation. 2021; 162: 329-333
- Incidence and outcome of out-of-hospital cardiac arrests in the COVID-19 era: a systematic review and meta-analysis.Resuscitation. 2020; 157: 248-258https://doi.org/10.1016/j.resuscitation.2020.10.025
- Collateral damage: Hidden impact of the COVID-19 pandemic on the out-of-hospital cardiac arrest system-of-care.Resuscitation. 2020; 156: 157-163https://doi.org/10.1016/j.resuscitation.2020.09.017
- Part 7: systems of care: 2020 American Heart Association Guidelines for cardiopulmonary resuscitation and emergency cardiovascular care.Circulation. 2020; 142https://doi.org/10.1161/CIR.0000000000000899
- Determining risk for out-of-hospital cardiac arrest by location type in a Canadian urban setting to guide future public access defibrillator placement.Ann Emerg Med. 2013; 61: 530-538https://doi.org/10.1016/j.annemergmed.2012.10.037
- Public access defibrillators: gender-based inequities in access and application.Resuscitation. 2020; 150: 17-22https://doi.org/10.1016/j.resuscitation.2020.02.024
- A smartphone application for dispatch of lay responders to out-of-hospital cardiac arrests.Resuscitation. 2018; 126: 160-165https://doi.org/10.1016/j.resuscitation.2018.01.039
- A text message alert system for trained volunteers improves out-of-hospital cardiac arrest survival.Resuscitation. 2016; 105: 182-187https://doi.org/10.1016/j.resuscitation.2016.06.006
- Local lay rescuers with AEDs, alerted by text messages, contribute to early defibrillation in a Dutch out-of-hospital cardiac arrest dispatch system.Resuscitation. 2014; 85: 1444-1449https://doi.org/10.1016/j.resuscitation.2014.07.020
- Mobile phone-based alerting of CPR-trained volunteers simultaneously with the ambulance can reduce the resuscitation-free interval and improve outcome after out-of-hospital cardiac arrest: a German, population-based cohort study.Resuscitation. 2020; 147: 57-64https://doi.org/10.1016/j.resuscitation.2019.12.012
- Improving response to out-of-hospital cardiac arrest: the verified responder program pilot.Resuscitation. 2020; https://doi.org/10.1016/j.resuscitation.2020.06.015
- Optimizing a drone network to deliver automated external defibrillators.Circulation. 2017; 135: 2454-2465https://doi.org/10.1161/CIRCULATIONAHA.116.026318
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Published online: February 14, 2021
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