Successful return of spontaneous circulation (ROSC) after out of hospital cardiac
arrest (OHCA) continues to depend on the ability to defibrillate the heart out of
ventricular fibrillation (VF).
1
Despite significant advances in signal processing technology and resuscitation care,
it remains difficult to accurately characterize ventricular fibrillation and to successfully
terminate VF. As demonstrated previously, the waveform characteristics of VF can be
altered by both the underlying pathology and by medications commonly used by patients
at risk for cardiac arrest.
2
,
3
,
4
Any attempts to use quantitative ventricular fibrillation waveform characteristics,
such as amplitude spectral area (AMSA), to predict a given patients chance of ROSC
after defibrillation, will require understanding the link between cardiac pathology,
medication use, and waveform morphology.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: April 15, 2020
Received:
April 1,
2020
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© 2020 Elsevier B.V. All rights reserved.