Advertisement
Clinical paper| Volume 151, P166-172, June 2020

The impact of resuscitation system factors on in-hospital cardiac arrest outcomes across UK hospitals: An observational study

      Abstract

      Purpose of the study

      To explore whether variation in in-hospital cardiac arrest (IHCA) survival can be explained by differences in resuscitation service provision across UK acute hospitals.

      Methods

      We linked information on key clinical practices with patient data of adults who had a cardiac arrest on a general hospital ward or emergency admissions unit in 2016/17. We used multi-level Bayesian models to explore associations between system quality indicators (number of resuscitation officers, audits time to first shock, review unexpected non-survivors, arrest team meets at handover, hot debrief, cold debrief, real-time audio-visual feedback, frequency of mock arrest provision) and adjusted hospital survival.

      Results

      We received survey responses from 110 out of 180 eligible hospitals (response rate 61%) relating to 12,285 cardiac arrest cases. Variation across trusts was observed in the number of resuscitation officers (median 0.7 (interquartile range 0.5, 0.9) per 750 clinical staff employed. Key system quality indicators were undertaken infrequently: audit of time to first shock (44.7%), arrest team meeting at handover (28.9%), mock arrests ≥ monthly (22.4%), and use of CPR feedback devices (18.4%). The probability that the system quality indicators had a positive effect on hospital survival ranged from 10% to 89%. However, there was uncertainty in the estimated odds ratios and we cannot exclude the possibility of a clinical benefit. Findings were consistent across secondary outcomes.

      Conclusion

      In this study, we identified variation in implementation of system quality indicators. Amongst hospitals that responded to our survey, the probability that individual factors increase the odds of hospital survival ranges from 10 to 89%.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Resuscitation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Couper K.
        • Kimani P.K.
        • Gale C.P.
        • et al.
        Patient, health service factors and variation in mortality following resuscitated out-of-hospital cardiac arrest in acute coronary syndrome: Analysis of the Myocardial Ischaemia National Audit Project.
        Resuscitation. 2018; 124: 49-57
        • Hawkes C.
        • Booth S.
        • Ji C.
        • et al.
        Epidemiology and outcomes from out-of-hospital cardiac arrests in England.
        Resuscitation. 2017; 110: 133-140
        • Chan P.S.
        • Krein S.L.
        • Tang F.
        • et al.
        Resuscitation practices associated with survival after in-hospital cardiac arrest: a nationwide survey.
        JAMA Cardiol. 2016; 1: 189-197
        • Ong M.E.H.
        • Shin S.D.
        • De Souza N.N.A.
        • et al.
        Outcomes for out-of-hospital cardiac arrests across 7 countries in Asia: The Pan Asian Resuscitation Outcomes Study (PAROS).
        Resuscitation. 2015; 96: 100-108
        • Ong M.E.H.
        • Perkins G.D.
        • Cariou A.
        Out-of-hospital cardiac arrest: prehospital management.
        Lancet. 2018; 391: 980-988
        • Wissenberg M.
        • Lippert F.K.
        • Folke F.
        • et al.
        Association of national initiatives to improve cardiac arrest management with rates of bystander intervention and patient survival after out-of-hospital cardiac arrest.
        JAMA. 2013; 310: 1377-1384
        • Couper K.
        • Kimani P.K.
        • Abella B.S.
        • et al.
        The system-wide effect of real-time audiovisual feedback and postevent debriefing for in-hospital cardiac arrest: the cardiopulmonary resuscitation quality improvement initiative.
        Crit Care Med. 2015; 43: 2321-2331
        • Lockey A.
        • Lin Y.
        • Cheng A.
        Impact of adult advanced cardiac life support course participation on patient outcomes—a systematic review and meta-analysis.
        Resuscitation. 2018; 129: 48-54
        • Wolfe H.
        • Zebuhr C.
        • Topjian A.A.
        • et al.
        Interdisciplinary ICU cardiac arrest debriefing improves survival outcomes.
        Crit Care Med. 2014; 42: 1688-1695
        • Carberry J.
        • Couper K.
        • Yeung J.
        The implementation of cardiac arrest treatment recommendations in English acute NHS trusts: a national survey.
        Postgrad Med J. 2017; 93: 653-659
        • Edelson D.P.
        • Yuen T.C.
        • Mancini M.E.
        • et al.
        Hospital cardiac arrest resuscitation practice in the United States: a nationally representative survey.
        J Hosp Med. 2014; 9: 353-357
        • Tirkkonen J.
        • Nurmi J.
        • Olkkola K.
        • Tenhunen J.
        • Hoppu S.
        Cardiac arrest teams and medical emergency teams in Finland: a nationwide cross-sectional postal survey.
        Acta Anaesthesiol Scand. 2014; 58: 420-427
        • Nolan J.P.
        • Soar J.
        • Smith G.B.
        • et al.
        Incidence and outcome of in-hospital cardiac arrest in the United Kingdom National Cardiac Arrest Audit.
        Resuscitation. 2014; 85: 987-992
        • Resuscitation Council (UK)
        Quality standards for cardiopulmonary resuscitation practice and training: acute care.
        2019 (Available at: https://www.resus.org.uk/quality-standards/acute-care-quality-standards-for-cpr/ [last accessed 8th January])
        • Resuscitation council (UK)
        Resuscitation guidelines 2015.
        2019 (Available at: https://www.resus.org.uk/resuscitation-guidelines/introduction/ [last accessed 8th January])
        • Harrison D.A.
        • Patel K.
        • Nixon E.
        • et al.
        Development and validation of risk models to predict outcomes following in-hospital cardiac arrest attended by a hospital-based resuscitation team.
        Resuscitation. 2014; 85: 993-1000
        • Jackson C.H.
        Displaying uncertainty with shading.
        Am Stat. 2008; 62: 340-347
        • Nallamothu B.K.
        • Guetterman T.C.
        • Harrod M.
        • et al.
        How do resuscitation teams at top-performing hospitals for in-hospital cardiac arrest succeed?. A qualitative study.
        Circulation. 2018; 138: 154-163
        • Bradley S.M.
        • Huszti E.
        • Warren S.A.
        • Merchant R.M.
        • Sayre M.R.
        • Nichol G.
        Duration of hospital participation in Get With the Guidelines-Resuscitation and survival of in-hospital cardiac arrest.
        Resuscitation. 2012; 83: 1349-1357
        • Starks M.A.
        • Dai D.
        • Nichol G.
        • et al.
        The association of Duration of participation in get with the guidelines-resuscitation with quality of Care for in-Hospital Cardiac Arrest.
        Am Heart J. 2018; 204: 156-162
        • Brown C.A.
        • Lilford R.J.
        The stepped wedge trial design: a systematic review.
        BMC Med Res Methodol. 2006; 6: 54