Abstract
Background
While survival after in-hospital cardiac arrest (IHCA) has improved in recent years,
it remains unknown whether this trend primarily applies to younger IHCA victims. The
aim of this study was to assess trends in survival to hospital discharge after adult
IHCA across age groups from 2000 to 2016.
Methods
This is an observational study of IHCA patients included in the Get With The Guidelines®-Resuscitation
registry between 2000 and 2016. The primary outcome was survival to hospital discharge.
Patients were stratified into five age groups: <50 years, 50–59 years, 60–69 years,
70–79 years, and ≥80 years. Generalized linear regression was used to obtain absolute
survival rates over time.
Results
A total of 234,767 IHCA patients were included. The absolute increase in survival
per calendar year was 0.8% (95% CI 0.7–1.0%, p < 0.001) for patients younger than
50 years, 0.6% (95% CI 0.4–0.7%, p < 0.001) for patients between 50 and 59 years,
0.5% (95% CI 0.4–0.6%, p < 0.001) for patients between 60 and 69 years, 0.5% (95%
CI 0.4–0.6%, p < 0.001) for patients between 70 and 79 years, and 0.5% (95% CI 0.4–0.6%,
p < 0.001) for patients older than 80 years. We observed a significant interaction
between calendar year and age group (p < 0.001), indicating that the rate of improvement in survival over time was significantly
different between age groups.
Conclusions
For patients with IHCA, rates of survival to discharge have improved significantly
from 2000 to 2016 across all age groups.
Keywords
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Article info
Publication history
Published online: April 01, 2020
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