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Editorial| Volume 149, P233-234, April 2020

No shocking updates for the lidocaine vs amiodarone in pediatric pVT/VF story

  • Janice Tijssen
    Affiliations
    Western University, Department of Paediatrics, 800 Commissioners Road East, London, ON, N6A 5W9, Canada

    Children's Hospital, London Health Sciences Centre, 800 Commissioners Road East, London, ON, N6A 5W9, Canada
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  • Allan DeCaen
    Correspondence
    Corresponding author at: University of Alberta, Pediatric Critical Care Medicine, Rm 4-539 (ECHA), 11405 87 Ave, Edmonton, AB T6G1C9, Canada.
    Affiliations
    University of Alberta, Pediatric Critical Care Medicine, Rm 4-539 (ECHA), 11405 87 Ave, Edmonton, AB T6G1C9, Canada

    Stollery Children’s Hospital, Pediatrics, Rm 4-539 (ECHA), 11405 87 Ave, Edmonton, AB T6G1C9, Canada
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      For the last 20 years, pediatric cardiac arrest guidelines have followed adult cardiac life support recommendations for the use of anti-arrhythmics due to an absence of high quality pediatric data.
      • Link M.S.
      • Berkow L.C.
      • Kudenchuk P.J.
      • et al.
      Part 7: adult advanced cardiovascular life support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.
      Most pediatric cardiac arrests are fundamentally different in etiology from adult cardiac arrests, suggesting the need for better evidence to support pediatric-specific treatment recommendations. In addition, the drugs in question are not without important side effects when used for some etiologies of pediatric shockable cardiac arrest (e.g. Amiodarone and Prolonged QT syndrome). For this reason, we applaud the investigators for researching this important topic and so rigorously analyzing the data.
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      References

        • Link M.S.
        • Berkow L.C.
        • Kudenchuk P.J.
        • et al.
        Part 7: adult advanced cardiovascular life support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.
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