For the last 20 years, pediatric cardiac arrest guidelines have followed adult cardiac life support recommendations for the use of anti-arrhythmics due to an absence of high quality pediatric data.
1Most pediatric cardiac arrests are fundamentally different in etiology from adult cardiac arrests, suggesting the need for better evidence to support pediatric-specific treatment recommendations. In addition, the drugs in question are not without important side effects when used for some etiologies of pediatric shockable cardiac arrest (e.g. Amiodarone and Prolonged QT syndrome). For this reason, we applaud the investigators for researching this important topic and so rigorously analyzing the data.
- Link M.S.
- Berkow L.C.
- Kudenchuk P.J.
- et al.
Part 7: adult advanced cardiovascular life support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.
Circulation. 2015; 132: S444-64
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- Part 7: adult advanced cardiovascular life support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.Circulation. 2015; 132: S444-64
- Outcomes associated with amiodarone and lidocaine in the treatment of in-hospital pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation.Resuscitation. 2014; 85: 381-386
- Lidocaine versus amiodarone for pediatric in-hospital cardiac arrest: an observational study.Resuscitation. 2020; 149: 191-201
- A randomized trial of epinephrine in out-of-hospital cardiac arrest.N Engl J Med. 2018; 379: 711-721
Published online: February 20, 2020
Received: February 7, 2020
© 2020 Elsevier B.V. All rights reserved.