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Sex differences in out-of-hospital cardiac arrest interventions within the province of British Columbia, Canada

  • Emad Awad
    Correspondence
    Corresponding author at: Department of Medicine, University of British Columbia, University of British Columbia, Experimental Medicine, Faculty of Medicine, 2775 Laurel Street, 10th Floor, Room 10117, Vancouver, BC, V5Z 1M9 Canada.
    Affiliations
    Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

    University of British Columbia, Experimental Medicine, Faculty of Medicine, 2775 Laurel Street, 10th Floor, Room 10117, Vancouver, BC, V5Z 1M9 Canada
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  • Jim Christenson
    Affiliations
    Department of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada

    St. Paul's Hospital, Vancouver, British Columbia, Canada

    University of British Columbia, Department of Emergency Medicine, Faculty of Medicine, Diamond Health Care Centre 11th floor, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada
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  • Brian Grunau
    Affiliations
    Department of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada

    St. Paul's Hospital, Vancouver, British Columbia, Canada

    Centre for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada

    University of British Columbia, Department of Emergency Medicine, Faculty of Medicine, Diamond Health Care Centre 11th floor, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada
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  • John Tallon
    Affiliations
    Department of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada

    BC Emergency Health Services (BCEHS), Vancouver, British Columbia, Canada

    Emergency Physician, Vancouver General Hospital, VCH, Vancouver, BC, Canada

    University of British Columbia, Department of Emergency Medicine, Faculty of Medicine, Diamond Health Care Centre 11th floor, 2775 Laurel Street,Vancouver, BC, V5Z 1M9, Canada
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  • Karin Humphries
    Affiliations
    Department of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada

    BC Centre for Improved Cardiovascular Health, Vancouver, British Columbia, Canada

    588 – 1081 Burrard Street, St. Paul’s Hospital,Vancouver, BC., V6Z 1Y6, Canada
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      Abstract

      Introduction

      Out-of-hospital cardiac arrest (OHCA) is common among females and males alike; however, previous studies reported differences in outcomes between sexes in different regions. To investigate possible explanations for this disparity, we examined sex differences in resuscitation interventions in the province of British Columbia (BC).

      Methods

      We performed an observational analysis of the BC Cardiac Arrest Registry (2011–16). We included adults with non-traumatic and EMS-treated OHCA. We examined sex differences in bystander CPR, chest compression rate, and intra-arrest transport using chi-square tests, student’s t-test, multivariable linear and logistic regressions.

      Results

      In total, 7398 patients were eligible for the bystander CPR analysis; 31% were female. More males received bystander CPR (54% vs. 50%); however, male sex was not associated with bystander CPR after adjustment for confounders (adjusted OR male vs. female: 1.07, 95% CI 0.96, 1.18).
      There was no difference in the chest compression rate for males and females in unadjusted or adjusted analyses.
      Among subjects who did not achieve prehospital ROSC (n = 5225, 32% females), 64% were pronounced dead at the scene with the remaining transported to hospital. Males more often underwent intra-arrest transport than females (36.7% vs. 34.0%). After adjustment, males had 1.2 greater odds of being transported to hospital than females (95% CI 1.04, 1.37).

      Conclusions

      We did not detect an association between sex and bystander CPR or chest compression rate. In those who did not achieve prehospital ROSC, males had 1.2-fold greater odds of being transported to hospital compared to females.

      Keywords

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