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Reply to: Ventilation during out-of-hospital cardiac arrest

      We thank Drs. Jo et al. for their interest in our study “Association of ventilation with outcomes from out-of-hospital cardiac arrest”.
      • Chang M.P.
      • Lu Y.
      • Leroux B.
      • et al.
      Association of ventilation with outcomes from out-of-hospital cardiac arrest.
      We agree with Jo et al.’s description of the components of ventilation during 30:2 CPR. They correctly state the median duration of pauses and the median number of ventilations in our study (Table 1).
      • Chang M.P.
      • Lu Y.
      • Leroux B.
      • et al.
      Association of ventilation with outcomes from out-of-hospital cardiac arrest.
      We wish to clarify that the median number of ventilations shown in Table 1 is not ventilations per pause, but instead is the total number of ventilations for the entire period of 30:2 CPR, which was a mean of 13 min. Likewise, the median number of pauses was the total number of pauses for the entire period of 30:2 CPR. On page 176, we defined a valid pause as one with durations lasting 3–15 s.
      Group 1 patients had a median total of 11 pauses and three ventilations over 13 min, while group two patients had a median total of 12 pauses and eight ventilations over 13 min. Few patients received more than two breaths in a single pause.
      We regret that we did not include the above details in Table 1 and we thank Jo et al. for giving us the opportunity to clarify these issues.

      Conflict of interests

      None.

      Acknowledgement

      This work was supported in part by NIH grant HL 077887 (AHI), MINECO project TEC2015-64678-R (EAE), and UPV_EHU grant GIU17/03 (EAE).

      Reference

        • Chang M.P.
        • Lu Y.
        • Leroux B.
        • et al.
        Association of ventilation with outcomes from out-of-hospital cardiac arrest.
        Resuscitation. 2019; 141 (PMID: 31112744): 174-181

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      • Ventilation during out-of-hospital cardiac arrest
        Resuscitation
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          We read with great interest the article by Chang MP, et al, which evaluated the bio-impedance ventilation (lung inflation) waveforms in the pause between chest compression segments among out-of-hospital cardiac arrest patients who received 30:2 compression ventilation (CV) ratio of cardiopulmonary resuscitation (CPR).1 They found survival improvement in patients with ventilation waveforms in ≥50% of pauses (Group 2) than in <50% of pause (Group 1). This finding is noteworthy because it showed ventilation metric would be included in one of high quality CPR components.
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