Abstract
Background
Our aim was to compare the efficacy of the end-tidal CO2-guided automated robot CPR (robot CPR) system with manual CPR and mechanical device
CPR.
Methods
We developed the algorithm of the robot CPR system which automatically finds the optimal
compression position under the guidance of end-tidal CO2 feedback in swine models of cardiac arrest. Then, 18 pigs after 11 min of cardiac
arrest were randomly assigned to one of three groups, robot CPR, LUCAS CPR, and manual
CPR groups (n = 6 each group). Return of spontaneous circulation (ROSC) and Neurological
Deficit Score 48 h after ROSC were compared.
Results
A ROSC was achieved in 5 pigs, 4 pigs, and 3 pigs in the robot CPR, LUCAS CPR, and
manual CPR groups, respectively (p = 0.47). Robot CPR showed a significant difference in Neurological Deficit Score
48 h after ROSC compared to manual CPR, whereas LUCAS CPR showed no significant difference
over manual CPR. (p = 0.01; Robot versus Manual adjusted p = 0.04, Robot versus LUCAS adjusted p = 0.07, Manual versus LUCAS adjusted p = 1.00).
Conclusions
The end-tidal CO2-guided automated robot CPR system did not significantly improve ROSC rate in a swine
model of cardiac arrest. However, robot CPR showed significant improvement of Neurological
Deficit Score 48 h after ROSC compared to Manual CPR while LUCAS CPR showed no significant
improvement compared to Manual CPR.
Keywords
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Article info
Publication history
Published online: April 14, 2018
Accepted:
April 10,
2018
Received in revised form:
March 21,
2018
Received:
January 27,
2018
Footnotes
☆A Spanish translated version of the abstract of this article appears as Appendix in the final online version at https://doi.org/10.1016/j.resuscitation.2018.04.011.
Identification
Copyright
© 2018 Elsevier B.V. All rights reserved.
