Abstract
Objective
To describe caregiver burden among those whose children survive in-hospital cardiac
arrest and have high risk of neurologic disability, and explore factors associated
with burden during the first year post-arrest.
Methods
The study is a secondary analysis of the Therapeutic Hypothermia after Paediatric
Cardiac Arrest In-Hospital (THAPCA-IH) trial. 329 children who had an in-hospital
cardiac arrest, chest compressions for >2 min, and mechanical ventilation after return
of circulation were recruited to THAPCA-IH. Of these, 155 survived to one year, and
caregivers of 138 were assessed for burden. Caregiver burden was assessed at baseline,
and 3 and 12 months post-arrest using the Infant Toddler Quality of Life Questionnaire
for children <5 years old and the Child Health Questionnaire for children >5 years.
Child functioning was assessed using the Vineland Adaptive Behaviour Scales Second
Edition (VABS-II), the Paediatric Overall Performance Category (POPC) and Paediatric
Cerebral Performance Category (PCPC) scales, and caregiver perception of global functioning.
Results
Of 138 children, 77 (55.8%) were male, 77 (55.8%) were white, and 109 (79.0%) were
<5 years old at the time of arrest. Caregiver burden was greater than reference norms
at all time points. Worse POPC, PCPC and VABS-II scores at 3 months post-arrest were
associated with greater caregiver burden at 12 months. Worse global functioning at
3 months was associated with greater burden at 12 months for children <5 years.
Conclusions
Caregiver burden is substantial during the first year after paediatric in-hospital
cardiac arrest, and associated with the extent of the child’s neurobehavioural dysfunction.
Keywords
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Article info
Publication history
Published online: March 27, 2018
Accepted:
March 26,
2018
Received in revised form:
March 14,
2018
Received:
January 25,
2018
Footnotes
☆A Spanish translated version of the abstract of this article appears as Appendix in the final online version at https://doi.org/10.1016/j.resuscitation.2018.03.034.
Identification
Copyright
© 2018 Elsevier B.V. All rights reserved.
