Abstract
Aim
The aim of our study was to assess the impact of coronary angiography (CAG) after
out-of-hospital cardiac arrest (OHCA) without ST-elevation (STE).
Methods
Prospective observational study of adult (age ≥ 18) OHCA of presumed cardiac etiology
from 1/01/2010–12/31/2014 admitted to one of 40 recognized cardiac receiving centers
within a statewide resuscitation network.
Results
Among 11,976 cases, 1881 remained for analysis after exclusions. Of the 1230 non-STE
cases, 524 (43%) underwent CAG with resultant PCI in 157 (30%). Survival in non-STE
cases was: 56% in cases without CAG; 82% in cases with CAG but without PCI; and 78%
in those with PCI (p < 0.0001). In cases without STE the aOR for survival with CAG
alone was 2.34 (95% CI 1.69–3.24) and for CAG plus PCI was 1.98 (95% CI 1.26–3.09).
The aOR for CPC 1/2 with CAG alone was 6.89 (95% CI 3.99–11.91) and for CAG plus PCI
was 2.95 (95% CI 1.59–5.47). After propensity matching, CAG was associated with an
aOR for survival of 2.10 (95% CI 1.30–3.55) and for CPC 1/2 it was 5.06 (95% CI 2.29–11.19).
Conclusion
In OHCA without STE, CAG was strongly and independently associated with survival regardless
of whether PCI was performed. The association between CAG and positive outcomes remained
after propensity matching.
Keywords
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References
- American Heart Association statistics C and stroke statistics S. heart disease and stroke statistics–2015 update: a report from the American Heart Association.Circulation. 2015; 131: e29-322
- Part 8: post-cardiac arrest care: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.Circulation. 2015; 132: S465-82
- How much is enough… what more is needed?.Circ Cardiovasc Interv. 2015; : 8
- Patients without ST elevation after return of spontaneous circulation may benefit from emergent percutaneous intervention: a systematic review and meta-analysis.Resuscitation. 2016; 108: 54-60
- Outcomes of comatose cardiac arrest survivors with and without ST-segment elevation myocardial infarction: importance of coronary angiography.JACC Cardiovasc Interv. 2015; 8: 1031-1040
- Early cardiac catheterization is associated with improved survival in comatose survivors of cardiac arrest without STEMI.Resuscitation. 2014; 85: 88-95
- Emergency percutaneous Coronary intervention in post-cardiac arrest patients without ST-segment elevation pattern: insights from the PROCAT II registry.JACC Cardiovasc Interv. 2016; 9: 1011-1018
- Combining therapeutic hypothermia and emergent coronary angiography in out-of-hospital cardiac arrest survivors: optimal post-arrest care for the best patient.Eur Heart J Acute Cardiovasc Care. 2015; 4: 579-588
http://quickfacts.Census.Gov/qfd/states/04000.html, Accessed 10-14-15.
- Establishing Arizona's statewide cardiac arrest reporting and educational network.Prehosp Emerg Care. 2008; 12: 381-387
- Minimally interrupted cardiac resuscitation by emergency medical services for out-of-hospital cardiac arrest.JAMA. 2008; 299: 1158-1165
- Chest compression-only CPR by lay rescuers and survival from out-of-hospital cardiac arrest.JAMA. 2010; 304: 1447-1454
- Effect of transport interval on out-of-hospital cardiac arrest survival in the OPALS study: implications for triaging patients to specialized cardiac arrest centers.Ann Emerg Med. 2009; 54: 248-255
- Statewide regionalization of postarrest care for out-of-hospital cardiac arrest: association with survival and neurologic outcome.Ann Emerg Med. 2014; 64: 496-506
- Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Council, New Zealand Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Councils of Southern Africa).Circulation. 2004; 110: 3385-3397
- Advanced statistics: missing data in clinical research–part 1: an introduction and conceptual framework.Acad Emerg Med. 2007; 14: 662-668
- Advanced statistics: missing data in clinical research–part 2: multiple imputation.Acad Emerg Med. 2007; 14: 669-678
- Multiple imputation for nonresponse in surveys.John Wiley & Sons, New York1987
- An introduction to propensity score methods for reducing the effects of confounding in observational studies.Multivar Behav Res. 2011; 46: 399-424
- Trends and outcomes of coronary angiography and percutaneous coronary intervention after out-of-hospital cardiac arrest associated with ventricular fibrillation or pulseless ventricular tachycardia.JAMA Cardiol. 2016; 1: 890-899
- Cardiac arrest: a treatment algorithm for emergent invasive cardiac procedures in the resuscitated comatose patient.J Am Coll Cardiol. 2015; 66: 62-73
Article info
Publication history
Published online: March 13, 2018
Accepted:
March 12,
2018
Received in revised form:
January 12,
2018
Received:
October 17,
2017
Footnotes
☆A Spanish translated version of the abstract of this article appears as Appendix in the final online version at https://doi.org/10.1016/j.resuscitation.2018.03.023.
Identification
Copyright
© 2018 Elsevier B.V. All rights reserved.