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Clinical paper| Volume 127, P21-25, June 2018

Association between coronary angiography with or without percutaneous coronary intervention and outcomes after out-of-hospital cardiac arrest

  • Tyler F. Vadeboncoeur
    Correspondence
    Corresponding author.
    Affiliations
    Department of Emergency Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, United States
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  • Author Footnotes
    1 Bureau of Emergency Medical Services, Arizona Department of Health Services, 150 N. 18th Avenue, #540, Phoenix, AZ 85007, United States.
    Vatsal Chikani
    Footnotes
    1 Bureau of Emergency Medical Services, Arizona Department of Health Services, 150 N. 18th Avenue, #540, Phoenix, AZ 85007, United States.
    Affiliations
    The Arizona Department of Health Services Bureau of Emergency Medical Services and Trauma System, Phoenix, AZ, United States
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  • Author Footnotes
    2 University of Arizona, PO Box 245057, 1501 N. Campbell, Tucson, AZ 85724-5057, United States.
    Chengcheng Hu
    Footnotes
    2 University of Arizona, PO Box 245057, 1501 N. Campbell, Tucson, AZ 85724-5057, United States.
    Affiliations
    Arizona Emergency Medicine Research Center, The University of Arizona College of Medicine, Tucson, AZ, United States
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  • Author Footnotes
    3 Department of Emergency Medicine, University of Arizona, Box 245057, 1501 N. Campbell, Tucson, AZ 85724-5057, United States.
    Danial W. Spaite
    Footnotes
    3 Department of Emergency Medicine, University of Arizona, Box 245057, 1501 N. Campbell, Tucson, AZ 85724-5057, United States.
    Affiliations
    Arizona Emergency Medicine Research Center, The University of Arizona College of Medicine, Tucson, AZ, United States
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  • Author Footnotes
    1 Bureau of Emergency Medical Services, Arizona Department of Health Services, 150 N. 18th Avenue, #540, Phoenix, AZ 85007, United States.
    ,
    Author Footnotes
    4 Address for reprints: Arizona Department of Health Services, 150 N 18th Avenue, Suite 540, Phoenix, AZ, United States.
    Bentley J. Bobrow
    Footnotes
    1 Bureau of Emergency Medical Services, Arizona Department of Health Services, 150 N. 18th Avenue, #540, Phoenix, AZ 85007, United States.
    4 Address for reprints: Arizona Department of Health Services, 150 N 18th Avenue, Suite 540, Phoenix, AZ, United States.
    Affiliations
    The Arizona Department of Health Services Bureau of Emergency Medical Services and Trauma System, Phoenix, AZ, United States

    Arizona Emergency Medicine Research Center, The University of Arizona College of Medicine, Tucson, AZ, United States

    The University of Arizona Sarver Heart Center, Tucson, AZ, United States
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  • Author Footnotes
    1 Bureau of Emergency Medical Services, Arizona Department of Health Services, 150 N. 18th Avenue, #540, Phoenix, AZ 85007, United States.
    2 University of Arizona, PO Box 245057, 1501 N. Campbell, Tucson, AZ 85724-5057, United States.
    3 Department of Emergency Medicine, University of Arizona, Box 245057, 1501 N. Campbell, Tucson, AZ 85724-5057, United States.
    4 Address for reprints: Arizona Department of Health Services, 150 N 18th Avenue, Suite 540, Phoenix, AZ, United States.

      Abstract

      Aim

      The aim of our study was to assess the impact of coronary angiography (CAG) after out-of-hospital cardiac arrest (OHCA) without ST-elevation (STE).

      Methods

      Prospective observational study of adult (age ≥ 18) OHCA of presumed cardiac etiology from 1/01/2010–12/31/2014 admitted to one of 40 recognized cardiac receiving centers within a statewide resuscitation network.

      Results

      Among 11,976 cases, 1881 remained for analysis after exclusions. Of the 1230 non-STE cases, 524 (43%) underwent CAG with resultant PCI in 157 (30%). Survival in non-STE cases was: 56% in cases without CAG; 82% in cases with CAG but without PCI; and 78% in those with PCI (p < 0.0001). In cases without STE the aOR for survival with CAG alone was 2.34 (95% CI 1.69–3.24) and for CAG plus PCI was 1.98 (95% CI 1.26–3.09). The aOR for CPC 1/2 with CAG alone was 6.89 (95% CI 3.99–11.91) and for CAG plus PCI was 2.95 (95% CI 1.59–5.47). After propensity matching, CAG was associated with an aOR for survival of 2.10 (95% CI 1.30–3.55) and for CPC 1/2 it was 5.06 (95% CI 2.29–11.19).

      Conclusion

      In OHCA without STE, CAG was strongly and independently associated with survival regardless of whether PCI was performed. The association between CAG and positive outcomes remained after propensity matching.

      Keywords

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