AS097| Volume 118, SUPPLEMENT 1, e40, September 2017

Histological changes of the heart following prolonged circulatory arrest treated with controlled automated reperfusion of the whole body

      Objectives: Sudden cardiac arrest (CA) is a common cause of death and persistent neurological dysfunction thereafter. Extracorporeal life support systems (ECLS) are increasingly used to stabilize circulation during cardio-pulmonary resuscitation (CPR). Beyond that, controlled reperfusion of the whole-body (CARL) has been described as advanced strategy in the treatment of CA, preventing neurological damage caused by ischemia/reperfusion injury after CA in a pig-model. In this study, histological changes of the myocardium in pigs were assessed, which were treated within different scenarios of CA, CPR, ECLS and CARL.
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