Objectives: Sudden cardiac arrest (CA) is a common cause of death and persistent neurological
dysfunction thereafter. Extracorporeal life support systems (ECLS) are increasingly
used to stabilize circulation during cardio-pulmonary resuscitation (CPR). Beyond
that, controlled reperfusion of the whole-body (CARL) has been described as advanced
strategy in the treatment of CA, preventing neurological damage caused by ischemia/reperfusion
injury after CA in a pig-model. In this study, histological changes of the myocardium
in pigs were assessed, which were treated within different scenarios of CA, CPR, ECLS
and CARL.
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© 2017 Published by Elsevier Inc.
