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Editorial| Volume 85, ISSUE 9, P1123-1124, September 2014

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Hyperoxia following cardiac arrest: How much is too much?

  • Keith Couper
    Correspondence
    Corresponding author at: Academic Department of Anaesthesia, Critical Care, Pain and Resuscitation, Heart of England NHS Foundation Trust, MIDRU, Birmingham Heartlands Hospital, Birmingham B9 5SS, United Kingdom.
    Affiliations
    Academic Department of Anaesthesia, Critical Care, Pain and Resuscitation, Heart of England NHS Foundation Trust, Birmingham, UK

    Warwick Medical School, University of Warwick, Coventry, UK
    Search for articles by this author
  • Joyce Yeung
    Affiliations
    Academic Department of Anaesthesia, Critical Care, Pain and Resuscitation, Heart of England NHS Foundation Trust, Birmingham, UK

    School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, UK
    Search for articles by this author
Published:July 04, 2014DOI:https://doi.org/10.1016/j.resuscitation.2014.06.026
Hyperoxia following cardiac arrest: How much is too much?
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      Mode of death after admission to an intensive care unit following cardiac arrest.
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      Forming part of the post-cardiac arrest syndrome, this pathophysiological process stems from the brain's unique susceptibility to both ischaemia and subsequent reperfusion.
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      • Neumar R.W.
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      Whilst the importance of post-resuscitation care has been recognised for many years, it is now ingrained in resuscitation practice through its inclusion as a link in the chain of survival.
      • Tagami T.
      • Hirata K.
      • Takeshige T.
      • et al.
      Implementation of the fifth link of the chain of survival concept for out-of-hospital cardiac arrest.
      Circulation. 2012; 126: 589-597
      , 
      • Negovsky V.A.
      The second step in resuscitation—the treatment of the ‘post-resuscitation’ disease.
      Resuscitation. 1972; 1: 1-7

      Keywords

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      References

        • Nolan J.P.
        • Soar J.
        • Smith G.B.
        • et al.
        Incidence and outcome of in-hospital cardiac arrest in the United Kingdom National Cardiac Arrest Audit.
        Resuscitation. 2014; 85: 987-992
        View in Article
        • Perkins G.D.
        • Cooke M.W.
        Variability in cardiac arrest survival: the NHS Ambulance Service Quality Indicators.
        Emerg Med J. 2012; 29: 3-5
        View in Article
        • Laver S.
        • Farrow C.
        • Turner D.
        • Nolan J.
        Mode of death after admission to an intensive care unit following cardiac arrest.
        Intensive Care Med. 2004; 30: 2126-2128
        View in Article
        • Nolan J.P.
        • Neumar R.W.
        • Adrie C.
        • et al.
        Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke.
        Resuscitation. 2008; 79: 350-379
        View in Article
        • Tagami T.
        • Hirata K.
        • Takeshige T.
        • et al.
        Implementation of the fifth link of the chain of survival concept for out-of-hospital cardiac arrest.
        Circulation. 2012; 126: 589-597
        View in Article
        • Negovsky V.A.
        The second step in resuscitation—the treatment of the ‘post-resuscitation’ disease.
        Resuscitation. 1972; 1: 1-7
        View in Article
        • Yeung J.
        • Couper K.
        • Giles S.
        • Perkins G.
        Advances in post resuscitation care.
        J Intensive Care Soc. 2010; 11: 112-117
        View in Article
        • Sunde K.P.
        • Pytte M.
        • Jacobsen D.
        • et al.
        Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest.
        Resuscitation. 2007; 73: 29-39
        View in Article
        • Wang C.-H.
        • Chang W.-T.
        • Huang C.-H.
        • et al.
        The effect of hyperoxia on survival following adult cardiac arrest: a systematic review and meta-analysis of observational studies.
        Resuscitation. 2014; 85: 1142-1148
        View in Article
        • Pilcher J.
        • Weatherall M.
        • Shirtcliffe P.
        • Bellomo R.
        • Young P.
        • Beasley R.
        The effect of hyperoxia following cardiac arrest – a systematic review and meta-analysis of animal trials.
        Resuscitation. 2012; 83: 417-422
        View in Article
        • Kuisma M.
        • Boyd J.
        • Voipio V.
        • Alaspää A.
        • Roine R.O.
        • Rosenberg P.
        Comparison of 30 and the 100% inspired oxygen concentrations during early post-resuscitation period: a randomised controlled pilot study.
        Resuscitation. 2006; 69: 199-206
        View in Article
        • Kilgannon J.
        • Jones A.E.
        • Shapiro N.I.
        • et al.
        Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality.
        J Am Med Assoc. 2010; 303: 2165-2171
        View in Article
        • Spindelboeck W.
        • Schindler O.
        • Moser A.
        • et al.
        Increasing arterial oxygen partial pressure during cardiopulmonary resuscitation is associated with improved rates of hospital admission.
        Resuscitation. 2013; 84: 770-775
        View in Article
        • Young P.
        • Pilcher J.
        • Patel M.
        • et al.
        Delivery of titrated oxygen via a self-inflating resuscitation bag.
        Resuscitation. 2013; 84: 391-394
        View in Article
        • de Jonge E.
        • Peelen L.
        • Keijzers P.
        • et al.
        Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated intensive care unit patients.
        Crit Care. 2008; 12: R156
        View in Article
        • Neumar R.W.
        Optimal oxygenation during and after cardiopulmonary resuscitation.
        Curr Opin Crit Care. 2011; 17: 236-240
        View in Article
        • Deakin C.D.
        • Nolan J.P.
        • Soar J.
        • et al.
        European resuscitation council guidelines for resuscitation 2010 section 4. Adult advanced life support.
        Resuscitation. 2010; 81: 1305-1352
        View in Article
        • O’Driscoll B.R.
        • Howard L.S.
        • Davison A.G.
        BTS guideline for emergency oxygen use in adult patients.
        Thorax. 2008; 63: vi1-vi68
        View in Article

      Article info

      Publication history

      Published online: July 04, 2014
      Received: June 25, 2014

      Identification

      DOI: https://doi.org/10.1016/j.resuscitation.2014.06.026

      Copyright

      © 2014 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.

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