| Editorials |
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Chest compressions: The good, the bad and the ugly
30 December 2011
Where exactly is the chest compression, where does it begin, when does it end, how deep does it go and at what rate are they performed? In short – how good or bad is the chest compression? These are s...
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Trygve Eftestøl
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143-144
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Ventilation pressure waveforms to detect oesophageal intubation – Do we need any more techniques?
16 December 2011
In this edition of Resuscitation Kalmar et al. present a novel method of detecting oesophageal intubation based on ventilation pressure waveforms. The arguments for tracheal intubation in emergency ca...
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Ed Morris
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145-146
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Extracorporeal life support for cardiac arrest due to pulmonary embolism: Further studies are needed
19 December 2011
Until recently, cardiopulmonary resuscitation (CPR) has represented the only method to support life in cardiac arrest. During CPR, artificial circulation is produced by chest compression while pulmona...
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Claudio Sandroni,
Vincenzo Palmieri
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147-148
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Prognostication after cardiac arrest: Time to change our approach
19 December 2011
Comprehensive post-resuscitation care and the implementation of therapeutic hypothermia (TH) have improved survival and neurological recovery in comatose victims of cardiac arrest (CA). Changes in the...
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Mauro Oddo
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149-150
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| Review Papers |
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Use of ice-cold crystalloid for inducing mild therapeutic hypothermia following out-of-hospital cardiac arrest
17 October 2011
Abstract: Objective: Out of hospital cardiac arrest (OHCA) results in a significant mortality and neurological disability in survivors. The application of mild therapeutic hypothermia (MTH) to patient...
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N. Arulkumaran,
R. Suleman,
J. Ball
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151-158
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Therapeutic hypothermia and prevention of acute kidney injury: A meta-analysis of randomized controlled trials
07 October 2011
Abstract: Background: Therapeutic hypothermia has been shown to reduce neurological morbidity and mortality in the setting of out-of-hospital cardiac arrest and may be beneficial following brain injur...
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Paweena Susantitaphong,
Mansour Alfayez,
Abraham Cohen-Bucay,
Ethan M. Balk,
Bertrand L. Jaber
et al.
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159-167
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| Commentary and Concepts |
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CPR policies and the patient's best interests
31 October 2011
Abstract: Standard hospital CPR policies in many countries require CPR to be attempted on all patients having a cardiac arrest unless a Not-for-CPR order is in place. It has recently been shown that t...
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Stuart McLennan
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168-170
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| Clinical Papers |
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A new way to analyze resuscitation quality by reviewing automatic external defibrillator data
07 November 2011
Abstract: Aims: High quality cardiopulmonary resuscitation (CPR) plays an important role in survival of out-of-hospital cardiac arrests (OHCAs). We have developed an algorithm to automatically identif...
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Lian-Yu Lin,
Men-Tzung Lo,
Wen-Chu Chiang,
Chen Lin,
Patrick Chow-In Ko,
Kuang-Hua Hsiung,
Jiunn-Lee Lin,
Wen-Jone Chen,
Matthew Huei-Ming Ma
et al.
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171-176
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A novel method to detect accidental oesophageal intubation based on ventilation pressure waveforms
31 October 2011
Abstract: Background: Emergency endotracheal intubation results in accidental oesophageal intubation in up to 17% of patients. This is frequently undetected thereby adding to the morbidity and mortali...
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Alain F. Kalmar,
Anthony Absalom,
Koenraad G. Monsieurs
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177-182
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Percutaneous cardiopulmonary support in pulmonary embolism with cardiac arrest
07 November 2011
Abstract: Objective: To assess the role of percutaneous cardiopulmonary support (PCPS) for the resuscitation of patients with massive pulmonary embolism (PE) with circulatory collapse. We also compare...
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Katsutaka Hashiba,
Jun Okuda,
Nobuhiko Maejima,
Noriaki Iwahashi,
Kengo Tsukahara,
Yoshio Tahara,
Kiyoshi Hibi,
Masami Kosuge,
Toshiaki Ebina,
Tsutomu Endo,
Satoshi Umemura,
Kazuo Kimura
et al.
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183-187
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Does therapeutic hypothermia benefit adult cardiac arrest patients presenting with non-shockable initial rhythms?: A systematic review and meta-analysis of randomized and non-randomized studies
10 August 2011
Abstract: Background: The benefit of therapeutic hypothermia (TH) for comatose adult patients with return of spontaneous circulation after cardiac arrest (CA) with non-shockable initial rhythms is unc...
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Young-Min Kim,
Hyeon-Woo Yim,
Seung-Hee Jeong,
Mary Lou Klem,
Clifton W. Callaway
et al.
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188-196
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Serum matrix metalloproteinases in patients resuscitated from cardiac arrest. The association with therapeutic hypothermia
19 August 2011
Abstract: Aim: To study the systemic levels of matrix metalloproteinases (MMP) -7, -8 and -9 and their inhibitor TIMP-1 in cardiac arrest patients and the association with mild therapeutic hypothermia...
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Johanna Hästbacka,
Marjaana Tiainen,
Marja Hynninen,
Elina Kolho,
Taina Tervahartiala,
Timo Sorsa,
Anneli Lauhio,
Ville Pettilä
et al.
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197-201
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Therapeutic hypothermia is associated with improved neurologic outcome and survival in cardiac arrest survivors of non-shockable rhythms
22 August 2011
Abstract: Background: Therapeutic hypothermia improves neurologic outcomes in patients resuscitated from cardiac arrest due to ventricular fibrillation. However, its role in patients with cardiac arre...
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Justin B. Lundbye,
Mridula Rai,
Bhavadharini Ramu,
Alireza Hosseini-Khalili,
Dadong Li,
Hanna B. Slim,
Sanjeev P. Bhavnani,
Sanjeev U. Nair,
Jeffrey Kluger
et al.
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202-207
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Relationship between blood, nasopharyngeal and urinary bladder temperature during intravascular cooling for therapeutic hypothermia after cardiac arrest
09 September 2011
Abstract: Objectives: Therapeutic hypothermia improves survival and neurological outcome in patients successfully resuscitated after cardiac arrest. Accurate temperature control during cooling is esse...
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Piotr Knapik,
Wojciech Rychlik,
Dominika Duda,
Renata Gołyszny,
Dawid Borowik,
Daniel Cieśla
et al.
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208-212
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Circulating cell-free DNA levels correlate with postresuscitation survival rates in out-of-hospital cardiac arrest patients
22 August 2011
Abstract: Early prediction of prognosis is helpful in cardiac arrest patients. Plasma cell-free DNA, which increases rapidly after cell death, is a novel biomarker for the prognosis of critical ill pa...
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Chien-Hua Huang,
Min-Shan Tsai,
Chiung-Yuan Hsu,
Huei-Wen Chen,
Tzung-Dau Wang,
Wei-Tien Chang,
Matthew Huei-Ming Ma,
Kuo-Liong Chien,
Shyr-Chyr Chen,
Wen-Jone Chen
et al.
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213-218
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| Simulation and Education |
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Influence of pre-course assessment using an emotionally activating stimulus with feedback: A pilot study in teaching Basic Life Support
19 September 2011
Abstract: Background: Cardiopulmonary resuscitation (CPR) mastery continues to challenge medical professionals. The purpose of this study was to determine if an emotional stimulus in combination with ...
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Stefan K. Beckers,
Henning Biermann,
Saša Sopka,
Max Skorning,
Jörg C. Brokmann,
Nicole Heussen,
Rolf Rossaint,
Jackie Younker
et al.
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219-226
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The effectiveness of ERC advanced life support (ALS) provider courses for the retention of ALS knowledge
03 October 2011
Abstract: Purpose: Out-of-hospital emergency physicians in Austria need mandatory emergency physician training, followed by biennial refresher courses. Currently, both standardized ERC advanced life s...
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Henrik Fischer,
Guido Strunk,
Stephanie Neuhold,
Daniel Kiblböck,
Helmut Trimmel,
Michael Baubin,
Hans Domanovits,
Claudia Maurer,
Robert Greif
et al.
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227-231
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| Experimental Papers |
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Facilitation of hypothermia by quinpirole and 8-OH-DPAT in a rat model of cardiac arrest
01 August 2011
Abstract: Aim of the study: Therapeutic hypothermia improves outcome after cardiac arrest. Dopamine D2 agonists and serotonin 5-HT1A agonists lower body temperature by decreasing the set-point. We inv...
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Andreas Schneider,
Peter Teschendorf,
Peter Vogel,
Nicolai Russ,
Jürgen Knapp,
Bernd W. Böttiger,
Erik Popp
et al.
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232-237
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Cardioprotective effect of therapeutic hypothermia at 34 °C against ischaemia/reperfusion injury mediated by PI3K and nitric oxide in a rat isolated heart model
29 August 2011
Abstract: Aim: Therapeutic hypothermia (TH) is widely used as a cardioprotective treatment for cardiac arrest. TH at 30–32°C during ischaemia and reperfusion has a cardioprotective effect. The aims of...
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Toshiaki Mochizuki,
Shuchun Yu,
Takasumi Katoh,
Katsunori Aoki,
Shigehito Sato
et al.
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238-242
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Effect of valproic acid on acute lung injury in a rodent model of intestinal ischemia reperfusion
08 August 2011
Abstract: Objectives: Acute lung injury (ALI) can develop during the course of many clinical conditions, and is associated with significant morbidity and mortality. Valproic acid (VPA), a well-known a...
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Kyuseok Kim,
Yongqing Li,
Guang Jin,
Wei Chong,
Baoling Liu,
Jennifer Lu,
Kyoungbun Lee,
Marc deMoya,
George C. Velmahos,
Hasan B. Alam
et al.
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243-248
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Effects of n-propyl gallate on neuronal survival after forebrain ischemia in rats
01 August 2011
Abstract: The aim of the study: The present study was conducted to assess the effects of intraperitoneal administration of n-propyl gallate (PG) on hippocampal neuronal survival after forebrain ischem...
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Yasunobu Kawano,
Masahiko Kawaguchi,
Kiichi Hirota,
Shinichi Kai,
Noboru Konishi,
Hitoshi Furuya
et al.
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249-252
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Treatment with beta-hydroxybutyrate and melatonin is associated with improved survival in a porcine model of hemorrhagic shock
22 August 2011
Abstract: Introduction: The neuroprotective ketone β-hydroxybutyrate (BHB) and the antioxidant melatonin have been found at elevated levels in hibernating mammals. Previous studies in rat models of he...
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Kristine E. Mulier,
Daniel R. Lexcen,
Elizabeth Luzcek,
Joseph J. Greenberg,
Gregory J. Beilman
et al.
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253-258
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Clinically plausible hyperventilation does not exert adverse hemodynamic effects during CPR but markedly reduces end-tidal PCO2
19 August 2011
Abstract: Aims: Ventilation at high respiratory rates is considered detrimental during CPR because it may increase intrathoracic pressure limiting venous return and forward blood flow generation. We e...
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Raúl J. Gazmuri,
Iyad M. Ayoub,
Jeejabai Radhakrishnan,
Jill Motl,
Madhav P. Upadhyaya
et al.
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259-264
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| Case Report |
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Neurologic recovery after therapeutic hypothermia in patients with post-cardiac arrest myoclonus
03 October 2011
Abstract: Early myoclonus in comatose survivors of cardiac arrest, even when it is not myoclonic status epilepticus (MSE), is considered a sign of severe global brain ischemia and has been associated ...
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Jason M. Lucas,
Michael N. Cocchi,
Justin Salciccioli,
Jessica A. Stanbridge,
Romergryko G. Geocadin,
Susan T. Herman,
Michael W. Donnino
et al.
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265-269
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| Letters to the Editor (online only) |
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Basic life support – Becoming more complex
03 November 2011
We read with interest the article of Adelborg et al. where lifeguards performed single rescuer cardiopulmonary resuscitation (CPR) in a simulated manikin scenario. Mouth-to-mouth ventilation resulted ...
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Peter Paal,
Elisabeth Gruber,
Hermann Brugger,
Gabriel Putzer
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e23
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Reply to Letter: Basic Life Support-becoming more complex
03 November 2011
We appreciate the letter by Paal et al. in response to our recent paper. The main finding of our study was that mouth-to-mouth ventilation reduces interruptions in chest compressions and results in a ...
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Kasper Adelborg,
Christian Dalgas,
Erik Lerkevang Grove,
Bo Løfgren
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e25-e26
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Heart fatty acid binding protein and myoglobin do not improve early rule out of acute myocardial infarction when highly sensitive troponin assays are used
04 November 2011
In the August issue of Resuscitation, Body et al. concluded that a combination of heart fatty acid binding protein (hFABP) and cardiac troponin could rule out acute myocardial infarction (AMI) with a ...
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Sally Aldous,
Chris Pemberton,
Richard Troughton,
Martin Than,
A. Mark Richards
et al.
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e27-e28
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Reply to Letter: Still FABP-ulous even with a more sensitive troponin assay
10 November 2011
We welcome the thoughtful response by Aldous et al. to our recent publication in Resuscitation and the presentation of some new evidence with regard to this fascinating biomarker. We agree that the an...
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Richard Body,
Simon Carley,
Kevin Mackway-Jones
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e29-e30
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Animations for teaching the recognition of cardiac arrest
23 November 2011
Rescuers often fail to recognize cardiac arrest. This causes a delay in starting cardiopulmonary resuscitation (CPR) and this decreases the victim's chances of survival. A common reason for not starti...
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Jasmeet Soar,
John Parry
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e31
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Response to letter of Sloth and Blaivas entitled “The future of cardiopulmonary resuscitation: What if a TEE probe could shock, sense and pace?” [Resuscitation 82 (2011) 1253]
24 October 2011
Drs. Sloth and Blaivas state: “A small inexpensive TEE probe capable of sensing, pacing and defibrillating in an ideal location just behind the heart could be used in multiple care settings, including...
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Richard E. Kerber
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e33
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Metabolic dysfunction in the post-resuscitation heart
03 November 2011
We read with great interest the article by Fang et al. about the ultrastructural changes observed in the myocardium of rats submitted to ventricular fibrillation and cardiopulmonary resuscitation (CPR...
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Luca Siracusano,
Viviana Girasole
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e35-e36
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| Corrections |
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Corrigendum to “A sternal accelerometer does not impair hemodynamics during piglet CPR” [Resuscitation 82 (9) (2011) 1231–1234]
24 August 2011
The authors regret that Table 1 was reproduced twice as both Tables 1 and 2 in the above article. The authors would like to apologise for any inconvenience caused. The correct appears below.
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Mathias Zuercher,
Ronald W. Hilwig,
Mike Gura,
Jon Nysaether,
Vinay M. Nadkarni,
Marc D. Berg,
Karl B. Kern,
Robert A. Berg
et al.
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270
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Erratum to “Pauses during CPR—Are breaks hindering our efforts?” [Resuscitation 82 (2011) 1379–1380]
30 November 2011
The recent editorial ‘Pauses during CPR—Are breaks hindering our efforts?’ indicated incorrectly that the study by Hoppu and colleagues was undertaken in Helsinki. In fact, this research was undertake...
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Patrick Braun,
Volker Wenzel
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271
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