Resuscitation
Volume 35, Issue 1 , Pages 3-7 , August 1997

Adenosine receptor antagonism in refractory asystolic cardiac arrest: results of a human pilot study1

  • Timothy J Mader

      Affiliations

    • Department of Emergency Medicine, Tufts University School of Medicine, Boston, MA, USA
    • Department of Emergency Medicine, Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 413 7843343; fax: +1 413 5968926; e-mail: doct@crocker.com or doct1630@aol.com.
  • ,
  • Patrick Gibson

      Affiliations

    • Department of Emergency Medicine, Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199, USA

Received 7 November 1996 ,Accepted 7 January 1997.

References 

  1. Ornato J, Peberdy M. The mystery of bradyasystole during cardiac arrest. Ann Emerg Med 1996; 27: 576–587.
  2. Emergency Cardiac Care Committees and Subcommittees. American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiac care. J Am Med Assoc 1992; 268: 2171–2302.
  3. Pepe P, Cobb L, Persse D, et al. Improved criteria for waiving resuscitation efforts for out-of-hospital primary cardiac arrest. Ann Emerg Med 1994; 23: 619 [abstract].
  4. Belardinelli L, Linder J, Berne R. The cardiac effects of adenosine. Prog Cardiovasc Dis 1989; 32: 73–97.
  5. Viskin S, Belhassen B, Roth A, et al. Aminophylline for bradyasystolic cardiac arrest refractory to atropine and epinephrine. Ann Intern Med 1993; 118: 279–281.
  6. Littman PA, WJ Haynes, et al. Aminophylline fails to improve outcome of cardiopulmonary resuscitation from prolonged ventricular fibrillation: a placebo-controlled, randomized, blinded experimental study. J Am Coll Cardiol 1994; 23: 1708–1714.
  7. Pepe P. Out-of-hospital resuscitation research: rationale and strategies for controlled clinical trials. Ann Emerg Med 1993; 22: 17–23.

PII: S0300-9572(97)01097-6

Resuscitation
Volume 35, Issue 1 , Pages 3-7 , August 1997