Resuscitation
Volume 81, Issue 5 , Pages 596-602 , May 2010

A randomized comparison of cardiocerebral and cardiopulmonary resuscitation using a swine model of prolonged ventricular fibrillation

  • Timothy J. Mader

      Affiliations

    • The Department of Emergency Medicine, Baystate Medical Center/Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, United States
    • Corresponding Author InformationCorresponding author. Tel.: +1 413 794 1661; fax: +1 413 794 8070.
    • ,
  • Adam R. Kellogg

      Affiliations

    • The Department of Emergency Medicine, Baystate Medical Center/Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, United States
    • ,
  • Joshua K. Walterscheid

      Affiliations

    • The Department of Emergency Medicine, Baystate Medical Center/Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, United States
    • ,
  • Cynthia C. Lodding

      Affiliations

    • The Department of Emergency Medicine, Baystate Medical Center/Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, United States
    • ,
  • Lawrence D. Sherman

      Affiliations

    • The Department of Emergency Medicine, St. Francis Hospital, Federal Way, WA, United States

Received 21 October 2009 ,Revised 14 January 2010 ,Accepted 18 January 2010.

References 

  1. Little CM, Paradis NA, Heard K. Prehospital interventions to improve neurological outcome following cardiac arrest. Semin Neurol. 2006;26:380–386
  2. Stiell IG, Wells GA, Field B, et al. Advanced cardiac life support in out-of-hospital cardiac arrest. N Engl J Med. 2004;351:647–656
  3. Wenzel V, Krismer AC, Arntz HR, Sitter H, Stadlbauer KH, Lindner KH. A comparison of vasopressin and epinephrine for out-of-hospital cardiopulmonary resuscitation. N Engl J Med. 2004;350:105–113
  4. Weisfeldt ML, Becker LB. Resuscitation after cardiac arrest: a 3-phase time-sensitive model. JAMA. 2002;288:3035–3038
  5. Aufderheide TP, Sigurdsson G, Pirrallo RG, et al. Hyperventilation-induced hypotension during cardiopulmonary resuscitation. Circulation. 2004;109:1960–1965
  6. Bobrow BJ, Clark LL, Ewy GA, et al. Minimally interrupted cardiac resuscitation by emergency medical services for out-of-hospital cardiac arrest. JAMA. 2008;299:1158–1165
  7. Rittenberger JC, Bost JE, Menegazzi JJ. Time to give the first medication during resuscitation in out-of-hospital cardiac arrest. Resuscitation. 2006;70:201–206
  8. Kern KB, Valenzuela TD, Clark LL, et al. An alternative approach to advancing resuscitation science. Resuscitation. 2005;64:261–268
  9. Ewy GA. Cardiocerebral resuscitation: the new cardiopulmonary resuscitation. Circulation. 2005;111:2134–2142
  10. Kellum MJ, Kennedy KW, Ewy GA. Cardiocerebral resuscitation improves survival of patients with out-of-hospital cardiac arrest. Am J Med. 2006;119:335–340
  11. Kellum MJ, Kennedy KW, Barney R, et al. Cardiocerebral resuscitation improves neurologically intact survival of patients with out-of-hospital cardiac arrest. Ann Emerg Med. 2008;52:244–252
  12. Garza AG, Gratton MC, Salomone JA, Lindholm D, McElroy J, Archer R. Improved patient survival using a modified resuscitation protocol for out-of-hospital cardiac arrest. Circulation. 2009;119:2597–2605
  13. Ewy GA. Do modifications of the American Heart Association guidelines improve survival of patients with out-of-hospital cardiac arrest?. Circulation. 2009;119:2542–2544
  14. Mader TJ. Prolonged cardiac arrest: a revised model of porcine ventricular fibrillation. Resuscitation. 2008;76:481–484
  15. Bayley R, Weinger M, Meador S, Slovis C. Impact of ambulance crew configuration on simulated cardiac arrest resuscitation. Prehosp Emerg Care. 2008;12:62–68
  16. Williams DM. 2005 JEMS 200-city survey. A benchmark for the EMS industry. JEMS. 2006;31:44–61100–1
  17. Dzwonczyk R, Brown CG, Werman HA. The median frequency of the ECG during ventricular fibrillation: its use in an algorithm for estimating the duration of cardiac arrest. IEEE Trans Biomed Eng. 1990;37:640–646
  18. Brown CG, Dzwonczyk R. Signal analysis of the human electrocardiogram during ventricular fibrillation: frequency and amplitude parameters as predictors of successful countershock. Ann Emerg Med. 1996;27:184–188
  19. Callaway CW, Sherman LD, Scheatzle MD, Menegazzi JJ. Scaling structure of electrocardiographic waveform during prolonged ventricular fibrillation in swine. Pacing Clin Electrophysiol. 2000;23:180–191
  20. Sherman LD, Callaway CW, Menegazzi JJ. Ventricular fibrillation exhibits dynamical properties and self-similarity. Resuscitation. 2000;47:163–173
  21. Callaway CW, Sherman LD, Mosesso VN, Dietrich TJ, Holt E, Clarkson MC. Scaling exponent predicts defibrillation success for out-of-hospital ventricular fibrillation cardiac arrest. Circulation. 2001;103:1656–1661
  22. Berg RA, Hilwig RW, Kern KB, Ewy GA. Precountershock cardiopulmonary resuscitation improves ventricular fibrillation median frequency and myocardial readiness for successful defibrillation from prolonged ventricular fibrillation: a randomized, controlled swine study. Ann Emerg Med. 2002;40:563–570
  23. Menegazzi JJ, Wang HE, Lightfoot CB, et al. Immediate defibrillation versus interventions first in a swine model of prolonged ventricular fibrillation. Resuscitation. 2003;59:261–270
  24. Menegazzi JJ, Callaway CW, Sherman LD, et al. Ventricular fibrillation scaling exponent can guide timing of defibrillation and other therapies. Circulation. 2004;109:926–931
  25. Sherman LD, Flagg A, Calaway CW, Menegazzi JJ, Hsieh M. Angular velocity: a new method to improve prediction of ventricular fibrillation duration. Resuscitation. 2004;60:79–90
  26. Callaway CW, Menegazzi JJ. Waveform analysis of ventricular fibrillation to predict defibrillation. Curr Opin Crit Care. 2005;11:192–199
  27. Sherman LD. The frequency ratio: an improved method to estimate ventricular fibrillation duration based on Fourier analysis of the waveform. Resuscitation. 2006;69:479–486
  28. Sherman LD. The LAC: an improvement in the scaling exponent method of ventricular fibrillation duration estimation based on autocorrelation of the waveform. http://shermld.home.comcast.net: 2007 [cited 2007 July, 19].
  29. Ewy GA. A new approach for out-of-hospital CPR: a bold step forward. Resuscitation. 2003;58:271–272
  30. Ewy GA, Kern KB. Recent advances in cardiopulmonary resuscitation: cardiocerebral resuscitation. J Am Coll Cardiol. 2009;53:149–157
  31. Nichol G, Thomas E, Callaway CW, et al. Regional variation in out-of-hospital cardiac arrest incidence and outcome. JAMA. 2008;300:1423–1431
  32. Yang L, Weil MH, Noc M, Tang W, Turner T, Gazmuri RJ. Spontaneous gasping increases the ability to resuscitate during experimental cardiopulmonary resuscitation. Crit Care Med. 1994;22:879–883
  33. Bernard SA, Gray TW, Buist MD, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002;346:557–563
  34. Fan KL, Leung LP. Prognosis of patients with ventricular fibrillation in out-of-hospital cardiac arrest in Hong Kong: prospective study. Hong Kong Med J. 2002;8:318–321
  35. Herlitz J, Engdahl J, Svensson L, Angquist KA, Young M, Holmberg S. Factors associated with an increased chance of survival among patients suffering from an out-of-hospital cardiac arrest in a national perspective in Sweden. Am Heart J. 2005;149:61–66
  36. Lombardi G, Gallagher J, Gennis P. Outcome of out-of-hospital cardiac arrest in New York City. The Pre-Hospital Arrest Survival Evaluation (PHASE) Study. JAMA. 1994;271:678–683
  37. Plaisance P, Adnet F, Vicaut E, et al. Benefit of active compression–decompression cardiopulmonary resuscitation as a prehospital advanced cardiac life support. A randomized multicenter study. Circulation. 1997;95:955–961
  38. Stiell IG, Wells GA, DeMaio VJ, et al. Modifiable factors associated with improved cardiac arrest survival in a multicenter basic life support/defibrillation system: OPALS Study Phase I results. Ontario Prehospital Advanced Life Support. Ann Emerg Med. 1999;33:44–50
  39. 2005 American Heart Association Guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2005;112-IV:57–66
  40. Bledsoe BE, Porter RS, Cherry RA. Airway management and ventilation in paramedic care principals and practice: introduction to advanced prehospital care. Upper Saddle River, NJ: Brady Prentice Hall Health; 2006;pp. 504–611
  41. Wang HE, Yealy DM. How many attempts are required to accomplish out-of-hospital endotracheal intubation?. Acad Emerg Med. 2006;13:372–377
  42. Wang HE, Simeone SJ, Weaver MD, Callaway CW. Interruptions in cardiopulmonary resuscitation from paramedic endotracheal intubation. Ann Emerg Med. 2009;54:645–652
  43. Minville V, Pianezza A, Asehnoune K, Cabardis S, Smail N. Prehospital intravenous line placement assessment in the French emergency system: a prospective study. Eur J Anaesthesiol. 2006;23:594–597
  44. Rittenberger JC, Menegazzi JJ, Callaway CW. Association of delay to first intervention with return of spontaneous circulation in a swine model of cardiac arrest. Resuscitation. 2007;73:154–160
  45. Lai CS, Hostler D, D’Cruz BJ, Callaway CW. Prevalence of troponin-T elevation during out-of-hospital cardiac arrest. Am J Cardiol. 2004;93:754–756
  46. Niemann JT, Stratton SJ, Cruz B, Lewis RJ. Endotracheal drug administration during out-of-hospital resuscitation: where are the survivors?. Resuscitation. 2002;53:153–157
  47. Fowler R, Gallagher JV, Isaacs SM, Ossman E, Pepe P, Wayne M. The role of intraosseous vascular access in the out-of-hospital environment (resource document to NAEMSP position statement). Prehosp Emerg Care. 2007;11:63–66

☆ A Spanish translated version of the abstract of this article appears as Appendix in the final online version at doi:10.1016/j.resuscitation.2010.01.013.

PII: S0300-9572(10)00055-9

doi: 10.1016/j.resuscitation.2010.01.013

Resuscitation
Volume 81, Issue 5 , Pages 596-602 , May 2010

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