Resuscitation
Volume 66, Issue 2 , Pages 237-239 , August 2005

Does hyperglycaemia precede the clinical onset of myocardial ischaemia?

  • Stephen R. Laver

      Affiliations

    • Department of Anaesthesia and Critical Care, Royal United Hospital, Combe Park, Bath BA1 3NG, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 1225 825057; fax: +44 1225 825061.
    • ,
  • Andrew Padkin

      Affiliations

    • Consultant in Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath, UK

Received 2 August 2004 ,Revised 21 January 2005 ,Accepted 3 February 2005.

References 

  1. Sewdarsen M, Jilal I, Vythilingum S, Govender G, Rajput MC. Stress hyperglycaemia is a predictor of abnormal glucose tolerance in Indian patients with acute myocardial infarction. Diabetes Res. 1987;6:47–49
  2. Oswal GA, Smith CCT, Betteridge DJ, Yudkin JS. Determinants and importance of stress hyperglycaemia in non-diabetic patients with myocardial infarction. Br Med J. 1986;293:917–922
  3. Bolk J, Van der Ploeg TJ, Cornel JH, Arnold AER, Sepers J, Umans VAWM. Impaired glucose metabolism predicts mortality after myocardial infarction. Int J Cardiol. 2001;79:207–214
  4. Capes SE, Hunt D, Malmberg K, Gerstein HC. Stress hyperglycaemia and the risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet. 2000;355:773–778
  5. Malmberg K for the DIGAMI Study Group. Prospective randomised study of intensive treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. Br Med J. 1997;314:1512–1515
  6. Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, et al. Intensive insulin therapy in critically ill patients. N Engl J Med. 2001;345:1359–1367
  7. Laver S, Preston S, Turner D, Mckinstry C, Padkin A. Implementing intensive insulin therapy: development and audit of the Bath insulin protocol. Anaesth Intensive Care. 2004;32:311–316
  8. Bernard C, Lecons de physiologie experimentale appliqué a la medicine. vol. 1. Paris: Balliere, 1855. p. 296–313.
  9. Müllner M, Sterz F, Binder M, Schreiber W, Deimel A. Laggner AN blood glucose concentration after cardiopulmonary resuscitation influences functional neurological recovery in human cardiac arrest survivors. J Cereb Blood Flow Metab. 1997;17:430–436
  10. Jonassen AK, Sack MN, Ole D, Yellon DM. Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signalling. Circ Res. 2001;89:1191–1198

☆ A Spanish translated version of the Abstract and Keywords of this article appears as Appendix at 10.1016/j.resuscitation.2005.02.005.

PII: S0300-9572(05)00122-X

doi: 10.1016/j.resuscitation.2005.02.005

Resuscitation
Volume 66, Issue 2 , Pages 237-239 , August 2005

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